Video caption: Label-free live cell imaging of a Preadipocyte cell where healthy mitochondria (long filaments) can be appreciated
Nanolive is happy to announce that we will participate with a talk and a booth in the “Targeting Mitochondria Congress” from 27th to 29th of October in Berlin.
The talk will take be hold on Monday October 28th at 3:40pm in the main lecture hall.
We are looking forward to meeting you there!
Non-invasive live cell imaging overcomes phototoxicity problem while imaging cellular metabolism processes
A major problem with current imaging techniques is phototoxicity that leads to the observation of perturbed dynamics. Consequently, the mitigation of phototoxicity leads to poor time resolution of time lapse approaches. This is particularly true for small organelles like mitochondria or lipid droplets that are extremely sensitive to photo-induced oxidation. Last but not least, the use of chemical or genetically-encoded fluorescent markers perturbs the targeted biological processes.
However, the 3D Cell Explorer overcomes this problematic as it injects in the sample ~100 times less energy (~0.2 nW/µm2) than light sheet microscopes that are the reference in the matter. With a resolution below 200 nm, it enables high resolution and high-frequency imaging even with sensitive material, giving access to organelle dynamics that were previously out of reach.
Read more on our dedicated mitochondria page here.
Read our latest news
Mesenchymal stem cells (MSCs) hold great promise for regenerative medicines such as cell therapy and tissue engineering (1,2). These approaches require cells to be grown in culture and differentiated into specific cell types such as osteoblasts (bone cells),...
Stem cells were isolated from the umbilical cord matrix and grown in culture for 14 days. At this stage most cells in the population are at the mature megakaryocyte stage and can start producing platelets in internal membranes present in their cytoplasm. In this...
Feature Client: Michal Cifra from the Institute of Photonics and Electronics Academy of Sciences (Czech Republic)
Dr. Michal Cifra is the young, dynamic team leader of the Bioelectrodynamics team at the Institute of Photonics and Electronics Academy of Sciences (Czech Republic). His lab has recently purchased Nanolive’s 3D Cell Explorer-fluo microscope and published his first...
3D CELL EXPLORER
Budget-friendly, easy-to-use, compact solution for high quality non-invasive 4D live cell imaging
3D CELL EXPLORER-fluo
Multimodal Complete Solution: combine high quality non-invasive 4D live cell imaging with fluorescence