Jobs

Open positions at Nanolive

Why working for Nanolive?

Nanolive has developed a disruptive technology that, for the first time ever, allows users to explore a living cell in 3D without damaging it.

Nanolive’s product grants access to a completely new experience of the dynamic, living cell. Our symbiosis of modern hardware and powerful software is a major milestone in the history of microscopy, which may change all the rules in the fields of education, biology, pharmaceutics, and cosmetics.

At this early stage, we are looking for candidates who are eager to take responsibility and be involved in important company decisions. We are thus offering a long-term employment with an attractive startup package. 

 

OPEN POSITIONS

Master Student in Life Sciences for Master's Project (duration 6 months)

Nanolive has developed a disruptive technology that, for the first time ever, allows users to explore a living cell in 3D without damaging it. Nanolive is looking for an enthusiastic Master’s Student in Life Sciences to work on a phototoxic project in our R&D department.

What we are looking for

We are looking for a motivated Master’s student in Life Sciences in order to investigate the phototoxic effect of holotomography on living cells during long time lapse imaging compared to fluorescence imaging. The goal is to gather, for the first time, concrete measurements of phototoxic effects on subtle cellular features, based on advanced image analysis of cell movies.

The project will last 6 months and should start before October 2018.

The role will be based out of our office near Lausanne in Switzerland, so only Swiss citizens or individuals with a permit to work in Switzerland are eligible.

Project

Phototoxicity is a problem in live cell imaging that is dramatically underestimated. The problem is rarely put in perspective1 but impacts thousands of scientific works, at least. To date, no definitive solution exists for doing high-content imaging without phototoxicity except the one we develop here at Nanolive!

Here is an extract of the linked article:

“But as discussed in the December Editorial, even fluorescence microscopy with low irradiation intensities can cause dangerous levels of phototoxicity that permanently damage the sample. Microscopists are aware of these concerns but there has been little effort to implement processes intended to reduce the likelihood of it compromising research study results”

Nanolive develops a holotomographic setup that suppresses the phototoxicity parameter by injecting at the sample ~100 times less energy (~0.01 nW/µm2) than light sheet microscopes (~1nW/µm2) that are the reference in the matter. Thus, we demonstrate that it is possible to do high-frequency, long-term live imaging even with sensitive material, such as cellular organelles or stem cells.

  1. Evanko, D. Is phototoxicity compromising experimental results? Nature Methods, methagora (2013). Available at: http://blogs.nature.com/methagora/2013/11/is-phototoxicity-compromising-experimental-results.html.

Interested?

Are you interested to conduct your Master’s Project with us at Nanolive? Please send us your full application including your cover letter and CV to mathieu@nanolive.ch.