Our groundbreaking approach offers a label-free, high-content imaging solution that transforms the way cellular health, death, and phenotypic responses are monitored and quantified. Unlike traditional cytotoxicity assays, Nanolive’s technology bypasses the limitations of end-point measurements and fluorescent reporters, providing real-time, kinetic insights without the need for harmful dyes. With unparalleled precision and sub-cellular resolution, our assay facilitates a deeper understanding of drug interactions, ensuring more predictive and translational research outcomes.
Discover phenotypic drug safety and toxicology evaluation with Nanolive’s LIVE Cytotoxicity Assay.
Discover how to:
- Enhance drug safety evaluations with unbiased, label-free quantification of cell health and death.
- Capture dynamic cellular responses with high-content, high-resolution imaging for insights beyond traditional assays.
- Automatically translate complex visual data into actionable, easy-to-understand metrics with machine learning
- Detect cell death mechanisms including apoptosis and necrosis label-free
- Accelerate drug screening in 96-well plates
Case Studies from the Investigative Toxicology Application Note
Discover the practical applications of Nanolive’s LIVE Cytotoxicity Assay through our detailed case studies. These examples illustrate the assay’s precision in analyzing cell health, death, and response to drugs, without the need for harmful dyes or labels. Learn how this approach provides clearer insights into cytotoxic effects, drug efficacy, and the mechanisms behind cell death, enhancing the accuracy of toxicological assessments and drug development processes.
Case Study 1: Drug screening in a 96-well plate
Utilizes HeLa cells to evaluate the cytotoxic effects of varying concentrations of camptothecin and chloroquine, demonstrating the assay’s compatibility with high-throughput formats and its ability to discern concentration-dependent cell death kinetics.
Case study 2: Detecting cell death mechanisms
Focuses on identifying apoptosis, primary necrosis, and secondary necrosis in 3T3 pre-adipocytes, showcasing the assay’s unique capability to monitor different cell death pathways simultaneously, offering insights into the inflammatory profiles of drugs.
Nanolive’s LIVE Cytotoxicity Assay revolutionizes investigative toxicology by delivering high-content, real-time data for high biological relevance. Access our application note to explore how this advanced technology can enhance your research and drive innovation in drug toxicology and safety studies.
Transform your research with Nanolive’s innovative solutions. For more information or to request a demo, contact us here.
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