Discover how Nanolive’s advanced LIVE Cytotoxicity Assay can transform your drug delivery research. This application note details how our innovative, label-free technology enables precise monitoring of cell health and death in response to drug treatment. Explore how our approach offers unparalleled insights into phenotypic responses, improving the predictive value of your assays and accelerating the path to clinical success.
Enhance your drug development with Nanolive’s label-free LIVE Cytotoxicity Assay
Discover how to:
- Measure cell death rate in cellular subpopulations, using only a single fluorophore
- Measure rate of drug uptake, or rate of endocytosis
- Quantify mRNA expression and therapeutic effects
- Capture detailed subcellular changes without the use of harmful dyes, to preserve sample integrity
- Distinguish between apoptosis and necrosis label-free
Case Studies from the Drug Delivery Application Note
Explore real-world applications of Nanolive’s technology through detailed case studies that highlight its practical benefits.
Case Study 1: Detecting selective killing of cells in co-culture
Investigate how our LIVE Cytotoxicity Assay differentiates between cancerous and non-cancerous cells in co-culture, and quantifies cell death kinetics in each subpopulation. Its ability to detect drug selectivity and off-target effects ensures more biologically relevant data.
Case study 2: Quantifying particle uptake
Learn how Nanolive’s LIVE Cytotoxicity Assay visualizes and quantifies the uptake of therapeutic particles, offering valuable information on drug delivery mechanisms and efficiency.
Case Study 3: Measuring expression and cytotoxic effects of mRNA therapeutics
Understand how our assay measures RNA expression and its cytotoxic impact simultaneously, offering robust data on the efficacy and safety of mRNA-based treatments.
Nanolive’s LIVE Cytotoxicity Assay equips researchers with advanced tools for drug discovery and cellular research. Access our application note to see how our technology can advance your scientific studies and support your preclinical success.
Transform your research with Nanolive’s innovative solutions. For more information or to request a demo, contact us here.
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