Scientific Publications

Peer Reviewed Articles, Conference Posters, Publications on Technology


A potential hydrodynamic mechanism for cytoplasmic transfer between mammalian cells: Cell-projection pumping

Authors: Hans Zoellner, Navid Paknejad, James Cornwell, Belal Chami, Yevgeniy Romin, Vitaly Boyko, Sho Fujisawa, Elizabeth Kelly, Garry W. LynchGlynn RogersKatia ManovaMalcolm A.S. Moore

Published in BioRxiv


Image-based analysis of living mammalian cells using label-free 3D refractive index maps reveals new organelle dynamics and dry mass flux

Authors: Patrick A. Sandoz, Christopher Tremblay, F. Gisou van der Goot, Mathieu Frechin

PLoS Biol. 2019 Dec; 17(12): e3000553

Published in PLOS Biology

E-Cigarette Use Increases Susceptibility to Bacterial Infection by Impairment of Human Neutrophil Chemotaxis, Phagocytosis and NET Formation

Authors: Ross Corriden, Alexander Moshensky, Christine M Bojanowski, Angela Meier, Jason Chien, Ryan K Nelson, Laura E. Crotty Alexander

Published in American Journal of Physiology

S-Nitrosothiol Plasma-Modified Surfaces for the Prevention of Bacterial Biofilm Formation

Authors: Zahra Sadrearhami, Rashin Namivandi-Zangeneh, Emily Price, Marta Krasowska, Sameer A Al-Bataineh, Jason Whittle, Edgar H. H. Wong, Anton Blencowe, Cyrille Boyer

ACS Biomater. Sci. Eng. 2019, 5, 11, 5881-5887

Published in ACS Publications

Toxoplasma gondii-induced host cellular cell cycle dysregulation is linked to chromosome missegregation and cytokinesis failure in primary endothelial host cells

Authors: Velásquez ZD, Conejeros , Larrazabal C , Kerner K, Hermosilla C, Taubert A.

Published in PubMed

Beyond the suprachiasmatic nucleus: circadian rhythmicity shapes astrocyte morphology and neuronal function in hippocampal area CA1

Authors: John P. McCauley, Maurice A. Petroccione, Lianna Y. D’Brant, Gabrielle C. Todd, Nurat Affinnih, Justin J. Wisnoski, Shergil Zahid, Swasti Shree, Alioscka A. Sousa, Rosanna Migliore, Alexey Brazhe, Richard D. Leapman, Alexander Khmaladze, Alexey Semyanov, Michele Migliore and Annalisa Scimemi

Published in bioRxiv

Autophagosome accumulation-mediated ATP energy deprivation induced by penfluridol triggers nonapoptotic cell death of lung cancer via activating unfolded protein response

Authors: Wen-Yueh Hung, Jer-Hwa Chang, Yu Cheng, Guo-Zhou Cheng, Hsiang-Ching Huang, Michael Hsiao, Chi-Li Chung, Wei-Jiunn Lee and Ming-Hsien Chien

Published in Springer Nature

Quantification of changes in cellular morphology during cell necrosis obtained from 3D refractive index distributions

Authors: D A Gorbenko, A V Belashov, T N Belyaeva, E S Kornilova, I V Semenova and O S Vasyutinskii

Published in Journal of Physics

Pleiotropic Effects of Epithelial Mesenchymal Crosstalk on Head and Neck Cancer: EMT and beyond

Authors: T. B. Steinbichler, D. Savic, D. Dejaco, A. Romani, B. Kofler, I. I. Skvortsova, H. Riechelmann, J. Dudas

Published in Cancer Microenvironment

Endocytosis-mediated mitochondrial transplantation: Transferring normal human astrocytic mitochondria into glioma cells rescues aerobic respiration and enhances radiosensitivity

Authors: Chao Sun, Xiongxiong Liu, Bing Wang, Zhenhua Wang, Yang Liu, Cuixia Di, Jing Si, Hongyan Li, Qingfeng Wu, Dan Xu, Ji Li, Gang Li, Yupei Wang, Fang Wang and Hong Zhang

Published in Theranostics

BA6 Induces Apoptosis via Stimulation of Reactive Oxygen Species and Inhibition of Oxidative Phosphorylation in Human Lung Cancer Cells

Authors: Meng-Hsuan Cheng, Hung-Ling Huang, Yen-You Lin, Kuan-HaoTsui, Pei-Chin Chen, Shu-Yu Cheng, Inn-Wen Chong, Ping-JyunSung, Ming-Hong Tai, Zhi-Hong Wen, Nan-Fu Chen, and Hsiao-Mei Kuo

Published in Oxidative Medicine and Cellular Longevity journal

Impact of the Food Additive Titanium Dioxide (E171) on Gut Microbiota-Host Interaction

Authors: Gabriela Pinget, Jian Tan, Bartlomiej Janac, Nadeem O. Kaakoush, Alexandra Sophie Angelatos, John O’Sullivan6, Yen Chin Koay, Frederic Sierro, Joel Davis, Shiva Kamini Divakarla, Dipesh Khanal, Robert J. Moore, Dragana Stanley, Wojciech Chrzanowski and Laurence Macia

Published in frontiers in Nutrition

Besnoitia besnoiti infection alters both endogenous cholesterol de novo synthesis and exogenous LDL uptake in host endothelial cells

Authors: Liliana M. R. Silva, Dieter Lütjohann, Penny Hamid, Zahady D. Velasquez, Katharina Kerner, Camilo Larrazabal, Klaus Failing, Carlos Hermosilla & Anja Taubert

Published in nature Scientific Reports

Methamphetamine-induced apoptosis in glial cells examined under markerfree imaging modalities

Authors: Lianna Y. D’Brant, Habben Desta, Ting Chean Khoo, Anna V. Sharikova, Supriya D. Mahajan, Alexander Khmaladze

Published in Journal of Biomedical Optics

Synthesis of fluorescent molybdenum nanoclusters at ambient temperature and their application in biological imaging

Authors: Amit Kumar Sharma, Sunil Pandey, Nallin Sharma, Hui-Fen Wu

Published in Science Direct

Diagnosing water treatment critical control points for cyanobacterial removal: Exploring benefits of combined microscopy, next-generation sequencing, and cell integrity methods

Authors: Arash Zamyadi, Caitlin Romanis, Toby Mills, Brett Neilan, Florence Choo, Lucila A., Coral, Deb Gale, Gayle Newcombe, Nick Crosbie, Richard Stuetz, Rita K. Henderson

Published in Science Direct

Antibiofilm Nitric Oxide Releasing Polydopamine Coatings

Authors: Zahra Sadrearhami, Farah Nabilah Shafiee, Kitty Ka Kit Ho, Naresh Kumar, Marta Krasowska, Anton Blencowe, Edgar H. H. Wong, and Cyrille Boyer

ACS Appl. Mater. Interfaces 2019, 11, 7, 7320-7329

Published in ACS Publications

Degradation of Mitochondria and Oxidative Stress as the Main Mechanism of Toxicity of Pristine Graphene on U87 Glioblastoma Cells and Tumors and HS-5 Cells

Authors: Sławomir Jaworski, Barbara Strojny, Ewa Sawosz, Mateusz Wierzbicki, Marta Grodzik, Marta Kutwin, Karolina Daniluk and André Chwalibog 

Int. J. Mol. Sci. 201920(3), 650

Published in Publishing International Journal of Molecular Sciences


Morphological changes in the ovarian carcinoma cells of Wistar rats induced by chemotherapy with cisplatin and dioxadet

Authors: A. A. Zhikhoreva, A. V. Belashov, V. G. Bespalov, A. L. Semenov, I. V. Semenova, G. V. Tochilnikov, N. T. Zhilinskaya, and O. S. Vasyutinskii

Vol. 9, Issue 11, pp. 5817-5827, (2018)

Published in OSA Publishing

Label free 3D analysis of organelles in living cells by refractive index shows pre-mitotic organelle spinning in mammalian stem cells

Authors: Patrick A Sandoz, Christopher Tremblay, Sebastien Equis, Sorin Pop, Lisa Pollaro, Yann Cotte, Gisou F van der Goot, Mathieu Frechin

Pre-published in bioRxiv

Label-Free Digital Holo-tomographic Microscopy Reveals Virus-Induced Cytopathic Effects in Live Cells

Authors: Artur Yakimovich, Robert Witte, Vardan Andriasyan, Fanny Georgi, Urs F Greber

Published in American Society for Microbiology

Parvalbumin alters mitochondrial dynamics and affects cell morphology

Authors: Lucia Lichvarova, Thomas Henzi, Dzhamilja Safiulina, Allen Kaasik, Beat Schwaller

Volume 75, Issue 24, pp 4643–4666

Published in: Springer Link

Superresolved and reference-free microparticle traction force microscopy (MP-TFM) reveals the complexity of the mechanical interaction in phagocytosis

Authors: Daan VorselenYifan WangMatthew J FooterWei CaiJulie A Theriot

Pre-published in bioRxiv

Live-stream characterization of cadmium-induced cell death using visible CdTe-QDs

Authors: Samira Filali, Alain Geloën, Vladimir Lysenko, Fabrice Pirot & Pierre Miossec

Published in: Scientific Reports 

Nanoparticles Based on Poly(trimethylene carbonate) Triblock Copolymers with Post-Crystallization Ability and Their Degradation in vitro

Authors: Lucie Reinišová, Filip Novotný, Martin Pumera, Katarína Kološtová, Soňa Hermanová

Volume 26, Issue 11, pp 1026–1034

Published in: Springer Link 

Enhancing the antimicrobial and antibiofilm effectiveness of silver nanoparticles prepared by green synthesis

Authors: Susan Oliver,  Harsha Wagh, Yuanli Liang, Shuang Yang  and  Cyrille Boyer*

Published in: Journal of Materials Chemistry B

Nitric Oxide-Loaded Antimicrobial Polymer for the Synergistic Eradication of Bacterial Biofilm

Authors: Rashin Namivandi-Zangeneh, Zahra Sadrearhami, Ali Bagheri, Maeva Sauvage-Nguyen, Kitty Ka Kit Ho,Naresh Kumar, Edgar H. H. Wong, and Cyrille Boyer

ACS Macro Lett. 2018, 7, 5, 592-597

Published in: ASC Macro Letter

The Effects of Polymer Topology and Chain Length on the Antimicrobial Activity and Hemocompatibility of Amphiphilic Ternary Copolymers

Authors: Rashin Namivandi Zangeneh, Rebecca J. Kwan, Thuy-Khanh Nguyen, Jonathan Yeow, Frances L. Byrne, Stefan H. Oehlers, Edgar Wong and Cyrille Boyer

Published in: Polymer Chemistry Journal


Facile preparation of full-color emissive carbon dots and their applications in imaging of the adhesion of erythrocytes to endothelial cells

Authors: Zhiqiang Lai, Xiaojuan Yang ,Aiqun Li, Youyi Qiu, Jiye Cai  and  PeiHui Yang

Published in: Journal of Materials Chemistry B

The selexipag active metabolite ACT-333679 displays strong anti-contractile and anti- remodeling effects, but low β-arrestin recruitment and desensitization potential

Authors: Gatfield J., Menyhart K., Wanner D., Gnerre C., Monnier L., Morrison K., Hess P., Iglarz M., Clozel M. and Nayler O.

Published in: The Journal of Pharmacology and Experimental Therapeutics


Live Single-cell Mass Spectrometry with Spatial Quantitation by Three-Dimensional Holographic and Tomographic Laser Microscopy

Authors: Ali A, Abouleila Y, Amer S, Furushima R, Emara S, Equis S, Cotte Y, Masujima T

2016 Volume 32 Issue 2 Pages 125-127

Published in: Analytical Sciences as Rapid Communication

Tomographic Holographic Microscopy for Nano-Scale Dose Calculation and Assessing Gold Nanoparticle Uptake in Live Cells

ASTRO 2016

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Grassberger C, Dinkelborg P, McNamara A, Schuemann J, McMahon S*, Willers H, Paganetti H, Wang M

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Marker-free phase nanoscopy

Nature Photonics, 2013

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„We introduce a microscopic method that determines quantitative optical properties beyond the optical diffraction limit and allows direct imaging of unstained living biological specimens. In established holographic microscopy, complex fields are measured using interferometric detection, allowing diffraction-limited phase measurements. Here, we show that non-invasive optical nanoscopy can achieve a lateral resolution of 90 nm by using a quasi-2π-holographic detection scheme and complex deconvolution. We record holograms from different illumination directions on the sample plane and observe subwavelength tomographic variations of the specimen. Nanoscale apertures serve to calibrate the tomographic reconstruction and to characterize the imaging system by means of the coherent transfer function. This gives rise to realistic inverse filtering and guarantees true complex field reconstruction. The observations are shown for nanoscopic porous cell frustule (diatoms), for the direct study of bacteria (Escherichia coli), and for a time-lapse approach to explore the dynamics of living dendritic spines (neurones).

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Nanomicroscopy for Live Cell tomography

The Handbook of Nanomedicine, Third Edition, 2017

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„Nanolive‘s Cell Explorer‘s technology enables determination of how light propagets through the cell [… ] Applications of this technology, which is commercially available, will enable discoveries on living cells and study of diseases as well as effects of drugs at cell level. It will be useful for recording celular uptake as well as localization of metal nanoparticles and assessments of cell exposure to nanoparticles.

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Characterising live cell behaviour: Traditional label-free and quantitative phase imaging approaches

The International Journal of Biochemistry & Cell Biology, 2017

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“2.2. Quantitative phase imaging:  Commercially-available QPI systems can be broadly classified according to the phase retrieval method utilised: (i) off-axis digital holography (PhiAB, Nanolive, Lyncee Tec, Tescan,1 Ovizio); (ii) wavefront sensing (Phasics); (iii) spatial light interference (Phi Optics); (iv) ptychography (Phasefocus).”

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