The Ultimate Live Cell Imaging Tool

With the 3D Cell Explorer, for the first time ever, you are free to perform long-term observations of your cells without any invasion and in a quantitative way, based on their own physical properties (refractive index). 


User Friendly

No special sample preparation

Our disruptive technology allows, for the first time, to explore instantly the inside of a living cell in 3D without the need for any labeling or other invasive methods. No risk for falsification, we measure the structure itself and not attached molecules.

No bleaching

You are able to take continuous images of your living cells as often and for as long as you want without worrying of any bleaching effect.

Infinite live cell imaging

Our laser light intensity is comparable with environmental light. No safety goggles required. Observe your cells as long as you wish in their natural state, no phototoxicity.

Top stage incubator friendly

The microscope stage is perfectly compatible with classical top stage incubators. You are able to observe your cell’s behaviour in their natural environment (e.g. 5% CO2 & 37°C). 


Compatible with live cell imaging consumables (dishes or slides).

Self calibration

Self-adjusts on environmental changes: you do not need to worry for any environmental change of your sample. The microscope self-adjusts on your sample and adapts to changes in the imaging condition.

Accessible sample stage

Open sample stage (60 mm). Change or move your samples easily.

Cell Friendly

No stains

No need to kill (fix) your cells and no need to intrude them by adding chemical markers.

No cell’s swelling

No labelling derived cell’s swelling.

No phototoxicity

Our 3D Cell Explorer uses a low power green laser light (λ = 520nm, 0.2mW/mm2). No photo-toxicity was observed even after days of continuous imaging in presence of a top stage incubator. 

No genetical modifications

No need to genetically modify your cells to make them express exogenous proteins in order to see them.

Discovery Friendly

No markers uncertainity

No result uncertainty due to stain efficiency or long linkers.

Quantitative 4D data

The different cell organelles have different compositions. The 3D Cell Explorer measures their different RI and allows quantitative analysis. Thus different RI which is detectable with our instrument.


You can compare our technology with other complementary technologies (e.g. Fluorescence, EM).


You will be able to investigate your cells as no one before

  • No alteration of their normal physiology
  • No time limitation
  • Digital stain your cell part of interest

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Explore our potential applications.