Take your cell research to the next dimension

 

Exceeding any label-free live cell imaging capabilities of any other microscope.

Take your cell research to the next dimension

 

Exceeding any label-free live cell imaging capabilities of any other microscope.

Nanolive microscopes

 Swiss high precision microscopes that look instantly inside label-free living cells in 3D

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3D CELL EXPLORER

Budget-friendly, easy-to-use, compact solution for high quality non-invasive 4D live cell imaging             

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3D CELL EXPLORER-fluo

Multimodal Complete Solution: combine high quality non-invasive 4D live cell imaging with fluorescence

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CX-A

Automated live cell imaging: a unique walk-away solution for long-term live cell imaging of single cells and cell populations

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At Nanolive, we focus on innovative product development at the highest standards to deliver a high precision and quality research device for our international customers.

Nanolive has been awarded with the Top 10 Innovations 2019 from The Scientist. Learn more.

Application Highlights

Stem cells 

With Nanolive’s live cell microscopes it is possible to perform endless live cell imaging at very high spatio-temporal resolution even on the most sensitive cells without damaging them.

Cell metabolism

Thanks to the Nanolive imaging capabilities, highlights of lipid droplets and mitochondria fine dynamics that were previously out of reach are clearly visible now.

Immuno-oncology

Nanolive’s 3D Cell Explorer opens the door for new observations and for long-term live cell imaging of the dynamic interactions between immune cells and cancer cells, at high resolution.

Latest News

Capturing the deposition and early growth of bone that occur during osteogenic differentiation

Osteogenesis is the process in which new layers of bone tissue are placed by osteoblast cells, capable of synthesizing and mineralization bone. Osteoblasts are differentiated from mesenchymal stem cells (MSCs), in a linear sequence progressing from osteoprogenitors cells to pre-osteoblasts, osteoblasts, and finally, osteocytes [1]. Progression between the different stages is regulated by various transcription factors, cytokines, growth factors and extracellular matrix (ECM) proteins, that...

Morphological changes during adenovirus infection in osteosarcoma cells

In this footage, obtained using Nanolive’s 3D Cell Explorer-fluo we observe the progression of GFP-labelled adenovirus in human bone osteosarcoma epithelial (U2OS) cells. Adenovirus is known to migrate to the nucleus of its host cell where it forms structures known as adenovirus replication compartments (AdRCs) - specialized nuclear microdomains that synthesize viral DNA and RNA. At the end of the infectious cycle, adenoviruses induce lysis of the host cell and go on to attack and propagate...

Perturbation of living cells with kinase inhibitors

Background In this case study, we expose cells to inhibitors or modulators of kinase activity and observe how the cells respond. Hyperactivity, malfunction or overexpression of kinases is the root cause of many human cancers, and so the development of kinase inhibitors targeting specific pathways has generated great interest as an anti-cancer treatment. Experimental approach 8 inhibitors or modulators of kinase activities were tested targeting: Akt, JNK, CDK2, RTK, PKA, JAK, mTOR and AMPK (see...

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