Our costumer Actelion publishes its work with the 3D Cell Explorer

We are proud to announce the publication of our customer’s work, Actelion Pharmaceuticals Ltd, in the prestigious Journal of Pharmacology and Experimental Therapeutics

 

Selexipag (Uptravi®) is a recently marketed drug for the treatment of pulmonary arterial hypertension (PAH), released by Actelion Pharmaceuticals Ltd. The manuscript demonstrating its efficacy is now published online and is freely available to the public.

The 3D Cell Explorer was used to successfully monitor the drug induced cell shape changes in real-time. The resulting cell movies they obtained are visible here. More images and videos are referenced in the paper.

Please also refer to the testimonial from our customer below.

Oliver Nayler, PhD

Head, Cardiovascular & Fibrosis Biology, Actelion Pharmaceuticals Ltd., Allschwil, Switzerland

“Actelion researchers were among the first to explore the potential of the Nanolive 3D Cell Explorer in cell biological applications within the pharmaceutical industry. We were very happy that the system is so easy to set-up (plug-and-play) and we are still amazed by the beautiful images it generates.

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 We mainly use the Cell Explorer to perform real time image acquisition and we follow compound activity in different cellular backgrounds. In a very short period of time, the 3D Cell Explorer has become very intensively used and we have found applications in several different disease areas – we would not want to be without this instrument.”