Porous membranes are intended on separation of larger molecules such as solid colloidal particles, large biomolecules (proteins, DNA, RNA) and cells from the filtering media and they are used in microfiltration, ultrafiltration, and dialysis applications. Usually we imagine membrane pores like parallel, nonintersecting cylindrical capillaries, in reality the pores structure could be a random network of the unevenly shaped structures of different sizes. The 3D Cell Explorer can be used to obtain crucial morphological information about their structure, thanks to a marker free, real-time 3D reconstruction.
One of the most prevalent types of CTC (Circulating Tumor Cell) enrichment technique is the filtration method. Those methods are based on physical properties that allow isolation of CTCs by size. Indeed, CTCs are generally larger in size than hematopoietic cells, so most of these cells pass through the filter whereas CTCs are retained.
The size-based isolation of CTCs was initially explored by using polycarbonate filters. Here is presented the acquisition of one of these filters.
Learn more about the 3D Cell Explorer
Read more about the 3D Cell Explorer here and learn how to use it in 1 minute in this video
Discover all the secrets of the 3D Cell Explorer on our Introductory webinar
Learn how to digitally stain your cells with our software STEVE, in 1 minute
Find out the story behind a great technology, product and company
Read our successful blog post about “First Mitosis in 3D and without stain @ Nanolive!!“
After cell division… Apoptosis vs Necrosis “Have you ever wondered how cells die“?
Follow your cells in motion. Monitor cell migration with the 3D Cell Explorer!
The 3D Cell Explorer acts now as a cell GPS. Follow your cells and monitor their speed in real-time!